Paternal Insulin-like Growth Factor 2 ( Igf2) Regulates Stem Cell Activity During Adulthood
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منابع مشابه
Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood
Insulin-like Growth Factor 2 (IGF2) belongs to the IGF/Insulin pathway, a highly conserved evolutionarily network that regulates growth, aging and lifespan. Igf2 is highly expressed in the embryo and in cancer cells. During mouse development, Igf2 is expressed in all sites where hematopoietic stem cells (HSC) successively expand, then its expression drops at weaning and becomes undetectable whe...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2017
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2016.11.035